Initiation and use of PD Medication

Initiation and use of PD medication - Variable Definition Table:

Field Name

Description

Values

on_levodopa Is subject taking levodopa? Yes
No
Unknown
Null
on_dopamine_agonist Is subject taking a dopamine agonist? Yes
No
Unknown
Null
on_other_pd_medications Is subject taking some other PD medication(s)? Yes
No
Unknown
Null
use_of_pd_medication Is subject on medication for PD? Yes
No
Unknown
Null
date_of_pd_medication_initiation Date Of PD Medication Initiation YYYY-MM format
pd_medication_start_date PD medication Start Date YYYY-MM format
date_of_pd_medication_recent_use Date of recent PD medication use YYYY-MM format

 

Tables that Reference this Variable:

  • PD Medical History
     

Data Type Information:

Field Name

Type

Mode

on_levodopa STRING NULLABLE
on_dopamine_agonist STRING NULLABLE
on_other_pd_medications STRING NULLABLE
use_of_pd_medication STRING NULLABLE
date_of_pd_medication_initiation STRING NULLABLE
pd_medication_start_date STRING NULLABLE
date_of_pd_medication_recent_use STRING NULLABLE


Curation Notations:

  1. PD medication names were aligned with the provided by CDH list of relevant pd medications and pd medication class.
  2. For PD medication start date (yyyy-mm) the earliest date from the list of pd medication names was used. Fields “CMINDC” (Indication), “DISMED” (PD Medication?), “CMTRT” (Med Name) in PPMI and BioFIND Concomitant_Medications.csv and Concomitant_Medication_Log.csv were used to extract pd medication name, clean and further align it with the list of relevant pd medications to determine STARTDT (start date).
Query Definition
PD_Medical_History.pd_medication_initiation_months_after_baseline is not null OR PD_Medical_History.use_of_pd_medication is not null

Clinical Data Forms Queried (available as a BigQuery Table and csv File)
PD_Medical_History

Criteria
pd_medication_initiation_months_after_baseline is not null
use_of_pd_medication is not null
OR

Query
SELECT left(participant_id, 2) Cohort, count(distinct participant_id) Count from `amp-pd-research.2021_v2_5release_0510.PD_Medical_History` WHERE pd_medication_initiation_months_after_baseline is not null OR use_of_pd_medication is not null GROUP BY Cohort ORDER BY Cohort